Sputum Cytology

Test Overview

Sputum cytology examines a sample of sputum (mucus) under a microscope to determine whether abnormal cells are present. Sputum is not the same as saliva. Sputum is produced in the lungs and in the airways leading to the lungs. Sputum has some normal lung cells in it. See an illustration of the lungs' airwaysClick here to see an illustration..

Sputum cytology may be done to help detect certain noncancerous lung conditions. It may also be done when lung cancer is suspected.

A sputum sample may be collected:

  • By a person coughing up mucus.
  • By breathing in a saltwater (saline) mist and then coughing.
  • During bronchoscopy, which uses a bronchoscope to look at the throat and airway.

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Author: Maria G. Essig, MS, ELSLast Updated: March 21, 2007
Medical Review: Caroline S. Rhoads, MD - Internal Medicine
Robert L. Cowie, MB, FCP(SA), MD, MSc, MFOM - Pulmonology

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